A Pharmacist Explains the Newest Schizophrenia Medication
A Pharmacist Explains the Newest Schizophrenia Medication I’ve got some huge Pharmacy news there is a new medication for schizophrenia and this is huge because this is a new mechanism of action so the name of the medication.
is called coeny and it contains xanomeline and trospium chloride again if I’m saying this wrong it’s because it’s new so these are going to be oral capsules that are used for the treatment of schizophrenia in adults but what makes it unique is that it targets coleric receptors not dopaminergic receptors and then since I’m a nerd I had to look at the package.
insert just to really understand what this medication does because there’s really nothing about it online so this medication works twofold so first is that it has xanomeline which is a muscarinic Agonist and then trospium.
which is a muscarinic antagonist then for dosing the recommended starting dose is going to be 50/20 Mig twice a day for at least 2 days and then going to increase the dose to 100 Mig by 20 Mig twice daily for at least 5 days and then with this medication you’re going to want to take it at least 1 hour before.
meal or at least 2 hours after a meal is going to have anti-cholinergic side effects but with this medication one of the benefits of targeting The muscarinic receptors which is like M1 and M4 instead of dopaminergic is going to be the side effect so as you can see most of the common side effects are like nausea dyspepsia constipation.
vomiting with those antis psychotics that work on dopamine you’re going to see different side effects which usually are not preferred like lip smacking you may see like Tremors but excited to see how this.
